Clean and devein one pound of large shrimp. Set up a working station.
In the first bowl combine flour, garlic powder, onion powder, and salt. In the second bowl add the 2 eggs and water, beat together. In the third bowl combine the breadcrumbs and Parmesan cheese
Dredge the shrimp in the flour. Shake off the excess flour. Dip the shrimp in the egg next. Then coat the shrimp with the breadcrumb Parmesan cheese mixture. Set the shrimp that are on a plate while completing the rest of the shrimp. You can work in batches doing these steps.
While preparing the shrimp add about 1/8 inch of oil into a heavy skillet and heat over medium heat.
Once the shrimp are coated and the oil is heated (I test the oil by dripping a couple of drops of water into it if it sizzles the oil is ready).
Work in batches when frying the shrimp, do not overcrowd the skillet. Fry the shrimp 2 to 3 minutes on each side or until golden brown. (If the shrimp start to brown too quickly adjust the heat).